The French businessman was forced to step down as the IMF's chief last year (11) after he was caught up in a hotel rape scandal. Charges against him were dropped, but the fall-out cost him his job and his marriage.
Adjani recently told French publication Journal de Dimanche the film, to be directed by Abel Ferrara, will be hard hitting, revealing, "It should be fascinating because we have a director who isn't French in charge and he's going to go where it hurts... With him, there's no risk of being politically correct."
And newswoman Sinclair is delighted with the casting.
She tells local paper Le Parisien she's a big fan of Adjani's 1988 movie Camille Claudel, in which the actress starred opposite Depardieu.
Sinclair tells the newspaper, "I like that woman a lot."
And Depardieu insists he won't be holding back anything as the disgraced businessman Strauss-Kahn - because he found him to be "arrogant" throughout the rape scandal.
Announcing the casting earlier this year (12), the actor said, "Because I don't like him I'm going to do it."
The Green Card star is to play the lead role in the biopic of France's disgraced former IMF chief Dominique Strauss-Kahn, has been accused of sexually assaulting a chambermaid and was questioned by police over an alleged prostitution ring.
Depardieu knows exactly how to play the scandal-hit Frenchman, because Strauss-Kahn displays traits he abhors in his countrymen.
The actor tells Swiss chat show RTS, "He's not loveable. I think he's a bit like all the French, a bit arrogant. I don't much like the French in any case. And he's very French - arrogant, smug.
"He's playable. I will do it because I don't like him... We can all have filthy thoughts, and it's well known these guys with huge power can be like that. But I will not try to inhabit the role too deeply as I have never been moved by people who have no dignity."
The film will be directed by Abel Ferrara.
Overshadowed by the mighty NYCC this past weekend was another New York celebration of movies: the Hamptons International Film Festival. In recent years, HIFF has been an early step in the rise to notoriety of films like the Oscar-winning Slumdog Millionaire and Golden Globe-winning The Wrestler. This year's HIFF offered a slew of promising films, winning a variety of awards. Below is a complete list of HIFF's award-winning films for 2011.
AUDIENCE AWARD NARRATIVE
The Artist, directed by Michael Hazanavicius
AUDIENCE AWARD DOCUMENTARY
Hard Times: Lost on Long Island, directed by Marc Levin
AUDIENCE AWARD WINNER FOR BEST SHORT
Two's a Crowd, directed by Jim Isler and Tom Isler
NARRATIVE JURY WINNER
The Fairy, directed by Dominique Abel, Fiona Gordon and Bruno Romy
DOCUMENTARY JURY WINNER
Laura, directed by Fellipe Barbosa
SHORT DOCUMENTARY JURY WINNER
The Strange Ones, directed by Christopher Radcliff and Lauren Wolkstein
THE KODAK AWARD FOR BEST CINEMATOGRAPHY
Without, directed by Mark Jackson
THE WOUTER BARENDRECHT PIONEERING VISION AWARD
Without, directed by Mark Jackson
THE VICTOR RABINOWITZ AND JOANNE GRANT AWARD FOR SOCIAL JUSTICE
You've Been Trumped, directed by Anthony Baxter
THE ALFRED P. SLOAN FOUNDATION FEATURE FILM PRIZE
Small, Beautifully Moving Parts, directed by Anne Howell and Lisa Robinson
THE BRIZZOLARA FAMILY FOUNDATION AWARD FOR A FILM OF CONFLICT AND RESOLUTION
The Bully Project, directed by Lee Hirsch
In addition to the outstanding films, the Hamptons International Film Festival also recognizes actors and actresses in a category called Breakthrough Performance Recipients. 2011's winners include:
Emily Browning for her performance in Sleeping Beauty
Alexander Skarsgard for his performance in Melancholia
Stine Fischer Christiansen for her performance in Cracks in the Shell
Ezra Miller for his performance in Another Happy Day
Shailene Woodley for her performance in The Descendants
Anton Yelchin for his performance in Like Crazy