The Vicky Cristina Barcelona star will be photographed wearing the 2012 Key To The Cure T-shirt, which will be sold in Saks Fifth Avenue stores this autumn (12) to raise money for the Women's Cancer Research Fund.
The fund benefits charities aiming to find innovative detection methods, better treatments and eventual cures for cancer.
Cruz says, "I am honoured to join the Entertainment Industry Foundation's Women's Cancer Research Fund and Saks Fifth Avenue to raise awareness for women's cancers. Cancer has affected each and every one of us in one way or another and I am thrilled to be involved with this wonderful cause."
Previous ambassadors for the annual initiative include Hollywood beauties Gwyneth Paltrow and Uma Thurman.
The Downton Abbey star found fame in the 1970s and has featured in more than 40 TV shows during her career, as well as films including Calendar Girls and Shaun of the Dead.
She was the guest of honour at a graduation ceremony from the Scarborough Campus of the University of Hull on Friday, when officials handed her a Doctor of Letters.
Wilton said, "I am absolutely delighted. It is a great honour."
You've got to love artists these days. With the advent of the interwebs, today's pop art is no longer Warhol's soup cans. It's Chicks With Steve Buscemi Eyes and Photoshop jobs of celebs looking fat and old.
Artist Danny Evans, of Planet Hiltron, has an amazing new one. Evans created an image of celebrity couple Kim Kardashian and Kanye West 20 years in the future (kind of like Lea Thompson in Back to the Future). He recently told the Daily Mail that he "presents them as duller versions of themselves — maybe a little frumpier, heftier or a little plainer."
But it's not the first time Kardashian has had her look changed in the name of "art." Remember this E! special Secret Celebrity with Nick Lachey? The reality star wore a homely prosthetic face and fooled fans. Check out the clip below (skip to the halfway point unless you want to watch a disguised Nick Lachey stripping):
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It's a Girl! Kourtney Kardashian 'Overjoyed' About Baby Penelope
Kim Kardashian and Kanye: Twins? Plus: Amazingly Awesome BET Awards GIFs
Kim and Kanye Photographed Together in NYC
Reality TV star Kourtney Kardashian gave birth to a daughter on Sunday morning (08Jul12) in Los Angeles.
Kim Kardashian's sister welcomed a little girl named Penelope Scotland, weighing in at seven pounds, 14 ounces ( 3.2 kilograms), at the city's Cedars-Sinai Medical Center.
The new arrival is Kardashian's second child with her longtime boyfriend Scott Disick.
She tells E! News, "Scott and I are overjoyed to welcome our precious angel Penelope Scotland Disick into our lives. We are forever blessed. Mommy and baby are resting comfortably."
The couple is already parents to two-year-old son Mason.
The socialite's sister Kim also expressed her joy at becoming an aunt again in a post on her official website. She writes, "Welcome to the world, Penelope Scotland Disick! Kourtney gave birth to a beautiful baby daughter on Sunday and the whole family is so thrilled to finally meet her! She is absolutely perfect! I am so excited to be an aunt again and can't wait to spoil little Penelope. I know Mason is going to be the best big brother in the whole world. Congratulations Kourtney and Scott."
The big screen beauty is one of the most glamorous women in the world, but when she's at home, she likes nothing better than creating healthy meals and keeping her house in order.
She tells Britain's Hello! magazine, "I'm a housewife and it's beautiful, the best thing in the world. I know how to cook and it's important to me to make fresh food every day. I don't do crazy diets, just the good Mediterranean food that I love because it's important to eat well.
"I'm good at cleaning too. I learnt that when I made the film Volver. My character was always cleaning the house, so when I started preparing for the role I would go to my mother's house and to my sister's house, and they were like, 'I think she has a fever, because I don't know why else she has come to clean my house today.''
"I don't think I would like to be married again, I've been married for a very long time during my life." Downton Abbey star Penelope Wilton is happy with her current relationship status after two failed marriages. Her last union ended in 2001.
The Desperate Housewives star began dating Penelope Cruz's singer brother last February (11), several months after separating from her basketball star husband Tony Parker over reports of infidelity.
The couple was thought to have ended its relationship in March (12) but put rumours to rest a month later (Apr12) by sharing a romantic meal in Hollywood and later jetting off to Seville, where they were spotted getting intimate on 17 June (12).
However according to a representative for Cruz, the two have now called it quits for good, reports UsMagazine.com.
"I would love to work with (Allen) 20 times. I'm fascinated by his personality. Even a day of press, which is not my favourite part of this job, he makes it so interesting and so fun." Spanish actress Penelope Cruz hopes to be cast in another Woody Allen movie after starring in Vicky Cristina Barcelona and To Rome With Love.
The actress submitted documents for a legal separation from James Huggins, her partner of 12 years, in Los Angeles County Superior Court in March (12).
However, it appears Miller has had a change of heart - she has since lodged papers in L.A. asking a judge to dismiss her previous filing, reports TMZ.com.
Miller, who was previously married to actor Will Arnett, married Huggins in 2000. The couple has two children.
"She's a little paranoid, just in general, and so for some time, every time she was going to fly, she would call me crying, saying, 'If I die, make sure that this goes to my brother and that that happens and this goes to this house, and the dog has to be taken care of by my sister', you know, all kinds of things, and she was just flying from New York to L.A. or something. It took a while for her to recover." Salma Hayek on trying to help pal Penelope Cruz overcome her irrational flying fears after the two actresses were caught up in an emergency landing drama in 2004.