The curtain was due to go up on the Bell Shakespeare Company show at the famous Sydney Opera House on Wednesday (04Apr12), but opening night has now been called off.
Dan Spielman, who plays the title role in the Shakespearean tragedy, is among those affected by the severe food poisoning outbreak, along with two other actors and assistant director John Kachoyan.
Two of the group were admitted to hospital for treatment and the others were bedridden for several days.
Three preview performances were also called off and opening night has been tentatively rescheduled for Thursday (05Apr12).
Bell Shakespeare General Manager, Christopher Tooher, says in a statement, "The condition of the four affected Company members is being constantly monitored. All are now showing significant signs of improvement... We are currently working with the New South Wales Food Authority regarding the source of the food poisoning."
Macbeth has long been shrouded in superstition, with stories of jinxes and curses befalling castmembers, and many in the theatre world believe the name is cursed so refer to it instead as "the Scottish play".