The Silence of the Lambs actor, 73, married 54-year-old Colombian born antiques dealer Stella Arroyave in 2003.
Hopkins has now revealed he was in a terrible state when he was first introduced to Arroyave, but her positive attitude helped him beat his demons.
He tells Britain's Seven magazine, "She met me 10 years ago when I was shut down. Shut down for some years. I didn't feel shut down at the time. I felt I was quite happy. But I was dealing with slight depression. Not trusting anyone. Certainly not trusting women.
"Everyday she wakes up happy. She's very positive about everything. I learned from her just to take life as it comes. So I live my life in non-expectation."
The Silence of the Lambs star enlisted the help of his third wife, Colombian-born Stella Arroyave, in 2008 to help him adopt a healthier lifestyle.
The actor admits he became hooked on fatty foods before embarking on an extreme diet, which is believed to be meat-free.
He says, "I was addicted to bread, cookies, whatnot. I love all the bad stuff."
Hopkins now enjoys a simple life revolving around healthy eating and plenty of exercise - although he admits his initial weightloss was so drastic, it surprised even himself.
Images of a frail-looking Hopkins in 2008 and 2009 sparked fears for his health, but he insists he's currently in the best shape of his life.
The star, 73, tells New York Post columnist Cindy Adams, "My wife's no dictator, but she said I must stick to a regimen. So I'm in the gym six days a week, I power walk, live on 800 calories a day. No pasta. No seconds. A sandwich occasionally. Now I'm a health nut.
"I lost too much, 75 pounds in two years. But I gained a little back in Europe (while shooting Woody Allen's You Will Meet a Tall Dark Stranger earlier this year (10))."
His strict new diet means he's no longer able to fit into most of his clothes, so he's donated his larger items to charity.
He says, "I can't get back into my wardrobe. I gave it all away to some mission. I tried tailoring the pants but they look ridiculous."
London-born Abigail is Hopkins' daughter by his first wife, Peta Barker. They were married for four years before divorcing in 1972 when Abigail was just a small child.
Abigail, now 40 and an actress, singer/songwriter and director, dropped out of university as a youngster and was treated for drug addiction.
She once told an interviewer that she blames her father's absence for her problems.
She said, “I came very close to killing myself. The root cause was the fact that my father and I had an intermittent relationship.
Silence of the Lambs star Hopkins, 71, is reportedly overjoyed after he was recently reunited with his daughter in the British capital, where he is working on a new Woody Allen film.
A pal of the actor tells Britain's Sunday Express newspaper that Hopkins will even be hosting a small party for Abigail's birthday on Thursday (20Aug09).
Shortly after leaving Abigail's mother, Hopkins married his second wife, production assistant Jennifer Lynton.
They split in 2002 and he is now married to his Colombian-born third wife, Stella Arroyave.
Top Story: Britney Spears Responds to Fred Durst's Comments
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The Clash Will Not Perform at Rock and Roll Hall of Fame Induction
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Anthony Hopkins Weds Again
Anthony Hopkins, best known as Hannibal "the Cannibal" Lecter, married antiques dealer Stella Arroyave in a private ceremony, Reuters reports. Hopkins, 65, and Arroyave, 46, tied the knot Saturday in a ceremony in Malibu attended by friends and family. The two had been dating for about two years. This is the actor's third marriage.
"The Twist" Songwriter Dies
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