| Had her big break as prostitute April Green in the 1970s in the Off-Broadway production of Hot L Baltimore, a role she reprised for the 1975 TV series of the same name. |
| Her role as Berta on the TV sitcom Two and A Half Men, for which she has received two Emmy nominations, was originally only supposed to be for a two-part episode. |
| Made her theatrical film debut in Sidney Lumet's Network (1976). |
| Though known for her long career in TV and film, the actress has won a OBIE Award, Theater World Award and Drama Desk Award for her stage work. |
| Had her first starring role, opposite Rip Torn, in Heartland (1979). |
| Was known for April's boisterous laugh and has said that for years people asked her to do the laugh. |
| Co-founded the Circle Repertory Theatre in New York City. |