The 64-year-old Judging Amy star will reprise the role of the opera diva next spring (11), The Manhattan Theatre Club announced on Wednesday (15Dec10).
She previously featured in the production at New York's Kennedy Center earlier this year (10).
Stephen Wadsworth will return as director.
Previews begin on 24 May (11) and it will open on 21 June (11).
Daly received a Tony for her performance in the 1989 revival of Gypsy. She was last seen on Broadway in David Lindsay-Abaire's 2006 play Rabbit Hole, which has since been turned into a movie by Nicole Kidman.