The Atonement star made the trip to Chad to support UNICEF, and she was stunned when she discovered the conditions youngsters are living in.
Footage of Knightley's trip aired in a U.K. TV special on Wednesday night (23May12), in aid of the upcoming Soccer Aid fundraiser, and showed the 27 year old touring a nutrition centre set up to help those in need.
She said, "This area is currently in the grips (sic) of one of the worst food crises in years. In an emergency like this, children are often the first to pay the price. UNICEF and their partners are here trying to tackle this catastrophic situation.
"They've set up this nutrition centre to provide direct and immediate care to children who are victims of the crisis."
Knightley met young children at the unit, and gasped in horror as she declared of one tot, "She's swollen so her whole body is swollen up, all around her eyes is full of liquid. As the body swells the skin shrinks so it splits."
She also urged viewers to hand over $8 (£5) donations, adding, "With your help UNICEF can save children's lives... please text the word 'Donate' to 70442."
The Soccer Aid match takes place in Manchester, England on Sunday (27May12) and will feature stars including Will Ferrell, Michael Sheen and Robbie Williams competing for charity.
The beloved Finding Nemo star has been named the recipient of the 15th annual accolade, which she will collect at a ceremony in Washington, D.C. in October (12).
Joking about her latest honour, DeGeneres says, "To get the same award that has been given to people like Bill Cosby, Tina Fey and Will Ferrell, it really makes me wonder... why didn't I get this sooner?"
Additional former trophy holders include Steve Martin, Billy Crystal and Whoopi Goldberg.
Like it or not, the buzziest news story of the week has been Time magazine's controversial breastfeeding cover. So, of course, it got the Saturday Night Live treatment it deserved last night on the Will-Ferrell-hosted episode.
In a gleefully biting Weekend Update segment, Seth Meyers dissects everything from the mom's expression ("Blue Steel") to the kid's camo pants ("You do realize there aren't enough camouflage pants in the world to hide from the blowback this kid is gonna experience.")
And then he goes there, comparing cover mom Jamie Lynn Grumet to the bats**t crazy "I breastfeed my 6-year-old" Queen from Game of Thrones. (Come on, we were all thinking it). Watch the hilarious clip below and sound off in the comments section. What do you think: Was the skewering funny? Mean-spirited? Or a bit of both? More: 'Time' Magazine's Controversial Breastfeeding Cover: Celebs React on Twitter'SNL' Recap: Will Ferrell Returns, Digital Shorts Get Star-Studded Celebration Celeb Mom's Craziest Behavior: 7 in the Spotlight SNL Time Cover
Neil Patrick Harris, Josh Duhamel, Zach Galifianakis and Will Ferrell hare also taped Word To Your Mother videos encouraging women to get screened as America celebrates Mother's Day this weekend.
The short clips, shot for cancer research organisation The Noreen Fraser Foundation, stress the importance of early detection in the fight against the deadly disease.
In her video, Kardashian says, "Taking care of your health is the best gift you can give yourself. So please remember, eat healthy, exercise and get screened."
And Segel jokes, "Hey, you obviously know who I am. I'm Jason Segel, star of TV and film. I've given you a lot of comedy and all I ask is you give me one thing in return. Go make an appointment for your mammogram or pap smear. It's the least you could do for all I've given you. Happy Mother's Day."
Funnyman Ferrell, who co-founded the comedy website Funny Or Die, won the best individual performance award for his impersonation of former president George W. Bush reacting to Osama bin Laden's death.
Gosling was honoured alongside Jim Carrey and Eva Mendes in the best comedy entry for their work on Funny Or Die's Drunk History Christmas.
John Hurt and Kiefer Sutherland's web series The Confession won best drama, while rocker/actress Juliette Lewis and Graydon Sheppard were hailed for their S**t Girls Say internet series.
Singer Bjork landed the artist of the year award for her interactive album, Biophilia.
The prizes will be handed out on 21 May at New York's Hammerstein Ballroom, and the winners will be restricted to five word acceptance speeches.
Actors Will Ferrell, Jack Black, and Neil Patrick Harris are among the stars who've recorded personal e-cards in celebration of America's upcoming Mother's Day (13May12). Each of the free, comedic greetings also feature a gentle reminder for women to get screened for breast cancer in a bid to stress the importance of early detection.
Will Ferrell, Billy Crystal and Zach Galifianakis are among the nominees for the upcoming Webby Awards, which celebrate the best of the internet. The prizegiving, in which winners have to give a five-word acceptance speech, takes place in New York on 21 May (12).
Will Ferrell recently confirmed his obnoxious newsman character will be returning to the big screen for a follow-up after several years of financial wrangling with bosses at the 2004 hit's studio Paramount Pictures.
The main cast, including Steve Carell, Paul Rudd and Christina Applegate, are all expected to return, and Wilson has also made it known he is eager to rejoin the cast - even though his Anchorman alter ego Frank Vitchard suffered debilitating injuries.
He tells Collider.com, "Somebody just told me (about Anchorman 2) last week.
"I had forgotten that I'd lost both my arms in the first one. It would be so fun to do it. I would love to do something on that."
A follow-up to 2004 cult comedy Anchorman: The Legend Of Ron Burgundy, which starred Ferrell as an obnoxious 1970s newsman, has long been mooted, but Ferrell has now revealed he is working on a sequel.
The actor appeared in character as Burgundy during an appearance on Conan O'Brien's America TV talk show on Wednesday (28Mar12) to announce the news to fans.
He said, "As of 09:00 Mountain Time, Paramount Pictures and myself, Ronald Joseph Aaron Burgundy, have come to terms on a sequel to Anchorman. It is official! There will be a sequel to Anchorman. There will be a sequel.”
It is not yet known if Ferrell's co-stars Steve Carell, Paul Rudd and Christina Applegate will be returning in the new film.
The quote, wrongly attributed to the Hollywood actor, suggested the woman who pelted Kim Kardashian with flour last week (22Mar12) was arrested more quickly than the killer of slain Martin.
The fake tweet, accompanied by a picture of the Men in Black actor and the account name @RealWillSmith, reads, "We live in America where a girl that threw flour on Kim Kardashian was arrested on site. But the man who killed Trayvon Martin is still free."
However, Smith does not have a known Twitter account, nor has he been quoted in public before making the statement, while it is not the first fake Twitter celebrity drama linked to Martin.
A tweet believed to have been written by Will Ferrell in support of a bogus anti-racism charity set up to reportedly honour the murdered teenager was exposed as a fake.
The Twitter.com post, sent via @RealFerrellWill on Saturday (24Mar12), suggested the writer would offer up $1 (62 pence) for every retweet of the message "R.I.P. Trayvon Martin", but the message did not come from the real Will Ferrell.
Martin was shot dead last month (Feb12) by a Neighbourhood Watch volunteer, who thought the Florida teenager was acting suspiciously as he walked through a gated community. The teen was reportedly unarmed.