The star is a frontrunner for an Academy Award nomination after critics handed him a trophy for his portrayal of British monarch King George VI.
The Social Network was also praised by L.A. film experts and went home with the Best Film and Best Screenplay honours. The Best Director award was tied between The Social Network's David Fincher and Carlos filmmaker Olivier Assayas.
Other winners included Mother star Kim Hye-ja, who won the Best Actress prize, while the Best Supporting Actor and Actress were given to Niels Arestrup for his role in A Prophet and Jacki Weaver for her turn in Animal Kingdom. Toy Story 3 won the Best Animation prize while the documentary honour went to Last Train Home.
The movie, which chronicles a mother's struggle to prove her mentally-challenged son's innocence against allegations of murder, won veteran star Kim Hye-ja the Best Actress accolade, while director Bong Joon-ho and co-writer Park Eun-kyo landed Best Screenplay.
Chinese filmmaker Lu Chuan was named Best Director for City of Life and Death, while Wang Xueqi took home the Best Actor award for his role in Bodyguards and Assassins.
Director Zhang Yimou was hailed for his outstanding contribution to Asian Cinema, while action man John Woo was handed the prize for top-grossing film director of 2009 for Red Cliff, and Bollywood superstar Amitabh Bachchan was presented with a lifetime achievement honour.