Portrayed Eleanor Roosevelt in Mira Nair's biopic, "Amelia," based on the life of Amelia Earhart
Joined the cast of "24" (FOX) in its seventh season, playing President Allison Taylor
Appeared opposite Ralph Fiennes, in the Broadway production of the "Faith Healer"
Starred as Sister Aloysius in the Boradway production of "Doubt"
Re-teamed with director M. Night Shyamalan for "The Village"
Appeared with Mel Gibson in the M. Night Shyamalan thriller "Signs"
Had featured role in "The Divine Secrets of the Ya-Ya Sisterhood"
Co-starred with Swoosie Kurtz in the Nora Ephron play "Imaginary Friends" on Broadway
Played the title role in the Broadway revival of "Major Barbara"
Co-starred with Brooke Shields in the Lifetime movie "What Makes a Family"
Had featured role in Wolfgang Petersen's "The Perfect Storm"
Returned to the stage as Josie Hogan in O'Neill's "A Moon for the Misbegotten"; earned a Best Actress Tony nomination
Played Hallie Flanagan in "Cradle Will Rock"; directed by Tim Robbins
Had pivotal role as a veterinarian in Robert Redford's "The Horse Whisperer"
Appeared on stage in Tina Howe's "Pride's Crossing"
Played deaf maid Lucy in Wade Allen's "Julian Po"
Lent her voice to the PBS documentary "The West"
Delivered a Tony Award-winning performance as the meek yet defiant Catherine Sloper in the hit Lincoln Center revival of Ruth and Augustus Goetz's 1947 drama "The Heiress"
Starred in 18-minute short, "Polio Water"; written and directed by Caroline Kava
Won acclaim for her performance in Paula Vogel's Off-Broadway play "The Baltimore Waltz"
Breakthrough stage role, playing the toughened and much abused ex-convict Liz Morden in Timberlake Wertenbaker's "Our Country's Good" on Broadway; earned her first Tony nomination
Played Lady Macduff in the Christopher Plummer-Glenda Jackson production of "Macbeth"
Made Broadway debut in "Stepping Out"; directed by Tommy Tune
Feature film debut in Paul Schrader's "Light of Day"; co-starred with Michael J. Fox and Joan Jett
First TV-movie, played Tina Crawford in "Alex: The Life of a Child" (ABC)
Made television debut in the failed detective pilot "O'Malley"