Though by no means the most eccentric of the Arquette clan, actor David Arquette earned a reputation in the 1990s and into the new millennium as one of Hollywood's most offbeat talents. After a lengthy apprenticeship in minor roles, he caught his big break as the lightweight but loveable sheriff Dewey in Wes Craven's "Scream" (1996); the character was so popular with audiences that producers revamped his death scene to include him in both sequels (1997 and 1999). The franchise's success - along with his long-running marriage to his "Scream" co-star Courteney Cox, which ultimately ended in 2010 - propelled him to stardom, though he seemed to prefer character parts like the former high school jock in "Never Been Kissed" (1999) or his unabashed wrestling fan in "Ready to Rumble" (2000). On occasion, he could be counted on for more restrained dramatic turns, as seen in "johns" (1996), "Dreams with the Fishes" (1997), which he also co-produced, and the grim Holocaust film "The Grey Zone" (2002). However, audiences seemed more tolerant of Arquette's wacky side, which got plenty of exposure through frantic ads for AT&T and a brief stint as the WCW World Heavyweight Champion. Whether he was serving as comic relief in the ring or reprising his role of Sheriff Dewey Riley for "Scream 4" (2011), Arquette always managed to keep fans intrigued about just what he was going to do next.