Although a classically trained actor with a number of impressive stage performances on his résumé, Kelsey Grammer was best known for playing the pompous, but ultimately likable psychiatrist Dr. Frasier Crane on two classic and award-winning sitcoms, "Cheers" (NBC, 1984-1993) and "Frasier" (NBC, 1993-2004). Prior to him landing the role that defined his career, Grammer was struggling on stage and in small roles to make a name for himself, while behind the scenes, suffering from numerous personal tragedies that befell both himself and his family. Perhaps as a means of coping with the seemingly unending string of deaths of loved ones, Grammer fell into a dependency on cocaine and alcohol, which he later attributed to his inability to cope after the rape and murder of his sister by a man released on the grounds of insanity. For years, Grammer struggled to cope with his addictions, while audiences saw little to nothing of his problems in their enjoyment of Frasier Crane. Entering rehab for the first time in 1990, Grammer eventually attained sobriety in 1996, well into his Emmy Award-winning run on "Frasier," largely considered to be one of the most successful television spin-offs of all time. After "Frasier" finally left the airwaves in 2004, Grammer was finally able to concentrate on other projects. Despite memorable performances in other sitcoms and in features, Grammer was indelibly linked to the beloved character he had played so convincingly for years.