Professional Children's School
Joined the cast of the sitcom "The Real O'Neals"
Nominated for the 2011 Primetime Emmy Award for Outstanding Lead Actress in a Comedy Series
Returned to TV to star in the FOX comedy "Raising Hope"
Performed a one-woman show called "Martha Plimpton Sings?"
Earned her third consecutive Tony nomination for her role in "Pal Joey"
Appeared in the Broadway play, "Top Girls"; received a Tony award nomination for Featured Actress in a Play
Cast in the play "The Coast of Utopia," a trilogy by Tom Stoppard; earned a Tony award nomination
Guest-starred on an episode of "7th Heaven" (WB); also received her first writing credit for a different episode that year entitled "Red Socks"
Nominated for an Emmy Award for her guest appearance on the television drama "Law & Order: Special Victims Unit" (NBC)
Starred in a Chicago stage production of "Hedda Gabler"
Made stage directorial debut with "Absolution," performed at Chicago's Steppenwolf Theatre Company
Had a recurring role in the television drama "ER" (NBC) as Meg Corwyn
Appeared in the ensemble film "200 Cigarettes"
Donned a dark wig to play Edward Furlong's sister in John Waters' "Pecker"
Won praise for leading role in "Eye of God"
Appeared in "The Defenders: Payback", the first of a projected series of TV-movies for Showtime
Portrayed the lesbian lover of radical feminist Valerie Solanas in the indie film "I Shot Andy Warhol"
First feature starring role, "Samantha"
Co-starred with Campbell Scott in Shakespeare's "Pericles, Prince of Tyre" at the Public Theater
Played the indignant teenage daughter of Dianne Wiest in "Parenthood"
Second film with River Phoenix, the Academy Award-nominated film, "Running on Empty"
Co-starred in the critically praised but commercially unsuccessful feature, "Shy People"
Critically lauded performance as the Reverend Spellgood's daughter in "The Mosquito Coast" starring Harrison Ford and her future real-life love interest, River Phoenix
First substantial film role, "The River Rat"
Breakthrough performance as Stef Steinbrenner in "The Goonies"
TV acting debut, "The Hand-Me-Down Kid"
Appeared in a Calvin Klein jeans commercial at age 11
Made film acting debut in a bit part in "Rollover"
Stage debut at age eight in "The Haggadah" at New York Public Theater
Was conceived while her parents Keith Carradine and Shelley Plimpton were performing together in the Broadway production of "Hair" in 1970.
Enrolled in her first acting workshop at age 9.
Dated the late actor River Phoenix during her teens, who helped convert her to vegetarianism.
Formed the production company Everything is Horrible.
Works with the 52nd Street Project, helping bring theater arts to kids from inner city areas.
"Well, some people think I have a fear of success. And they might be right. I've always been at a weird age. When the John Hughes thing was happening, I was too young for that. Now I'm seen as too old for a lot of these other things, these things that Claire Danes does and stuff. And she's great. I like her a lot. I'm sort of out of the loop all the time. I'm either one step too early or one step too late. There's not one set of rules that I follow. Mainly what I do is turn down lots of crap until I get really poor. And then I start taking the crap." - from The A.V. Club, March 3, 1999