Panou was an actor who had a successful Hollywood career. He also was featured in the miniseries "Degree of Guilt" (1995-96) and "Steve Martini's Undue Influence" (1996-97). He worked in television in his early acting career as well, including a part on "La Femme Nikita" (USA, 1996-2001). He also starred in the TV movies "Elvis Meets Nixon" (Showtime, 1996-97) and "Every 9 Seconds" (NBC, 1997-98). He continued to work steadily in television throughout the nineties and the early 2000s, appearing on "I Was a Sixth Grade Alien" (Fox Family Channel, 1999-2001) and "Supernatural" (2005-). His work around this time also included a part on the TV movie "Ultimate Deception" (USA, 1998-99). More recently, he earned a role in "Eight Below" (2006). Panou focused on film in more recent years, appearing in the Hugh Jackman box office smash action film "X-Men Origins: Wolverine" (2009), the Aaron Eckhart drama "Love Happens" (2009) and the James Franco blockbuster action picture "Rise of the Planet of the Apes" (2011). He also appeared in "Underworld: Awakening" (2012) with Kate Beckinsale and "This Means War" (2012) with Reese Witherspoon. Panou most recently acted in the dramatic adaptation "Horns" (2014) with Daniel Radcliffe.