Before she joined the cast of "Mad Men" in 2007 as the sexy and smart Joan, Hendricks starred in "Hunger Point," a 2003 drama about a mother obsessed with controlling her daughters' weights.
Also released in 2003, this Academy Award-winning actress played a mother who starts dealing drugs to support her family, eventually becoming addicted to crystal meth. Mrs. Walter White?
Two years before Swank took home the Academy Award for her performance in "Boys Don't Cry," she played a sorority pledge subjected to brutal hazing like eating broken glass in "Dying to Belong." Ouch.
The talk show host returns to acting in this year's "A Day Late and a Dollar Short" about a matriarch facing the end of her life who is determined to restore her family before her passing.
Ricci, a former child star, brought the infamous Lizzie Borden to life in 2014's "Lizzie Borden Took an Ax." It was her first TV movie in more than a decade, but she has always excelled as the creepy character.
Four years after she got to lock lips on the big screen with Brad Pitt in "Interview with a Vampire," Dunst starred in the small-screen drama "Fifteen and Pregnant."
The same year Cuoco made her debut on "The Big Bang Theory" (2007), she starred in "To Be Fat Like Me" as a student who wheres a fat suit for a film project. From Lifetime to a $90-million contract? Now that's an upgrade.
Burstyn has been acting since the 1970s, but her most notable performance as of late was 2014's "Flowers in the Attic." She was, without a doubt, the grandmother from hell.
Chenoweth is a Tony Award-winning darling of Broadway and a popular guest star on "Glee," but back in 2009 she tried her hand at playing a tough publicist from New York who finds love in Montana in "12 Men of Christmas."
Before she became tough-as-nails Red on "Orange Is the New Black," Mulgrew played a wife and mother who walks away from her family in 1991's "Daddy," based on a Danielle Steel novel. Harsh.
Welch the legendary sex symbol and film star, took on the role of Aunt Lucia in the much-panned "House of Versace," which premiered in 2013. She looked fantastic, though.
Baxter, everyone's favorite mom, took on a much darker role in "A Woman Scorned: The Betty Broderick Story." Released in 1992, Baxter became the last woman you would ever want to mess with.
Marcia Gay Harden
Harden has an Oscar and much acclaim from her time on Broadway, but in 2004, she took her talents to the small screen to play the mother of a 14-year-old girl who becomes sexually active with an older student who may have HIV.
Back in 1996, Russell, who currently stars in the FX drama "The Americans," took on another scandalous role as a teenage babysitter seduced by a grieving father. This also makes her the lead suspect in the mother's murder.
In 2000's "The Truth About Jane," Channing plays a mother who struggles with accepting her daughter is gay. Like any good Lifetime movie, she comes around though. Way to go, Rizzo!