The Mirisch brothers began as producers with the "Bomba" series of low-budget films starring Johnny Sheffield – formerly 'Boy' in the "Tarzan" movies – as well as with action and Western movies. As Allied Artists head of production, Mirisch also supervised such classics as "Invasion of the Body Snatchers" (1956). When they opened their own shop, the Mirisch Company at first offered Westerns, beginning with "Fort Massacre" (1958) and "Gunfight at Dodge City" (1958) before soon becoming more ambitious.
Mirisch was executive producer of "The Magnificent Seven" (1960), the same year the Mirisch Company produced Billy Wilder's "The Apartment," which won the Best Picture Oscar. The Mirisch Company's 1961 release, "West Side Story," also won the Oscar for Best Picture. In 1967, Mirisch, himself, produced the Academy Award-winning Best Picture, "In the Heat of the Night," starring Rod Steiger as a Southern sheriff forced to forge a relationship and take help from a northern African-American police lieutenant (Sidney Poitier). With his proven track record, Mirisch continued producing motion pictures into the 1970s, including an ambitious rendition of "Dracula" (1979).
Although the Mirisch brothers had produced NBC’s 1959 series "Wichita Town" starring Joel McCrea, the company did not delve into television production on a regular basis until the 1980s, when Mirisch was executive producer of a series of "Desperado" TV movies. The company remained active in TV into the next decade, and in 1996 offered "A Case for Life," a telefilm about two sisters – one who is pregnant and is against abortion; the other who is pro-choice.
Key directors associated with The Mirisch Company during the golden years included Billy Wilder, John Huston, Blake Edwards and Norman Jewison. Notable films produced directly by Mirisch or which he supervised include "Fiddler on the Roof" (1971), "The Russians are Coming, the Russians are Coming" (1968), "The Pink Panther" (1964), "The Children's Hour" (1964), "Some Like It Hot" (1959) and "Toys in the Attic" (1963). Mirisch was also known for his many activities in the entertainment industry. He served four terms as the president of the Academy of Motion Picture Arts and Sciences, and three terms as president of the Producers Guild of America.