Detmer made greater strides in 2000, with a featured role in the ensemble of the teen thriller "Final Destination". Playing Terry, the agreeable girlfriend of thickheaded jock Carter (Kerr Smith) offered her increased visibility and the chance to suffer what may be the most genuinely startling demise in the contemporary spate of teen scream films. While her character would no doubt stay down, Detmer saw her profile continue to rise that year, starring as an understanding and upbeat teacher with a regular role on Don Roos' edgy comedy "M.Y.O.B." (NBC) and taking on a co-starring role alongside hot tickets Claire Forlani, Freddie Prinze Jr. and Jason Biggs in Robert Iscove's college-set romantic comedy "Boys and Girls". In 2001, she reteamed with Biggs, playing his love interest (and a would-be nun) in the daffy comedy "Saving Silverman".