Born on June 30, 1971 in Cleveland, OH, Potter was raised the second oldest of four daughters by her father, Paul Brokaw, an inventor who created the first fire-retardant car wax, and her mother, Nancy, a former cleaning woman and secretary. From a very early age, Potter knew that she wanted to be an actress. Her parents were immediately supportive; even submitting photos of their daughter to a local talent agent. When she was 12, Potter began landing regular work in commercials, including one for shoe shine spray. Meanwhile, she grew up like any other American kid, attending the Catholic Villa Angela High School for girls before graduating from the public Euclid High School. After high school, she went to Chicago, then Miami in pursuit of her dream, modeling and appearing in television commercials along the way. In 1994, she moved to Los Angeles with her first husband, Tom Potter, where she began the usual rounds of auditions and taking acting classes.
Eventually, Potter appeared in a chewing gum commercial directed by acclaimed French filmmaker, Luc Besson. Credited as her first major breakthrough, Potter landed representation at a top talent agency, which led to a regular stint on the long-running soap opera, “The Young and the Restless” (CBS, 1973- ), briefly playing Sharon Abbott for a couple of months. Soon she made her feature film debut as a biker girl in “Bulletproof” (1996), which she followed with a small role as the wife of Nicolas Cage in the action thriller, “Con Air” (1997). She had a larger part in “Heaven or Vegas” (1997), playing the younger sister of an exotic dancer and prostitute (Yasmine Bleeth) struggling for a way out of her dead-end existence. In the excruciatingly sappy “Patch Adams” (1998), she was a young medical student who attracts the amorous attention of an unorthodox physician (Robin Williams) who heals patients with laughter. Potter’s first meaty role came with writer-director Robert Towne’s “Without Limits” (1998), in which she played the college love interest of Steve Prefontaine (Billy Crudup), the legendary Olympic long-distance runner who died in a car accident while at the peak of his talent.
After playing an American woman who catches the eye of three British men (Joseph Fiennes, Tom Hollander and Rufus Sewell) in "Martha, Meet Frank, Daniel and Laurence" (1998), Potter landed another substantial starring role in "A Cool Dry Place" (1999), playing the estranged wife of a Dallas lawyer (Vince Vaughn) who tries to reintegrate herself into their son’s life. She next starred opposite Freddie Prinze, Jr. in "Head Over Heels" (2001), an awkward blend of romantic comedy and thriller in which she played a so-called normal girl with four supermodel roommates who is dating a man she suspects of harboring a dark secret. Meanwhile, Potter was tapped to join Morgan Freeman for the crime thriller "Along Came a Spider" (2001), the second film featuring him as forensic psychologist Alex Cross. Potter played a Secret Service agent who pushes her way into Cross' investigation of a politician's kidnapped daughter after failing to keep the girl safe. But her talents were underused and she failed to receive the same breakout boost Ashley Judd had with the first installment, “Kiss the Girls” (1997).
Potter took a turn into romantic comedy territory with "I'm With Lucy" (2002), playing a woman about to be married who recounts for her best friend her experiences with five blind dates, one of whom ultimately becomes her groom. Although her film career did not seem to be delivering on Potter's early potential, thanks in part to run-of-the-mill projects that failed to attract much attention, she nonetheless remained a regular face in features, playing Cary Elwes’ estranged, suspicious wife in the brutal horror film, "Saw" (2004). Meanwhile, she established herself on television, co-starring in David E. Kelly's snarky lawyer series "Boston Legal" (ABC, 2004- ) as Lori Colson, a principled, slightly unconfident attorney working alongside more ethically-challenged colleagues. After playing a prosecuting attorney in “Scott Turnow’s Reversible Errors” (CBS, 2004), a legal thriller about a defense lawyer (William H. Macy) trying to get an innocent, mentally challenged man (Glenn Plummer) off death row, Potter continued her role on “Boston Legal” in a recurring fashion.
Returning to film, she co-starred in “Lower Learning” (2008), then starred in a new series, “Trust Me” (TNT, 2009), a drama that focused on the happenings at a Chicago advertising agency. She next played a concerned mother who hatches a plan to avenge her teenage daughter’s brutal rape in “The Last House on the Left” (2009).