Following his daytime work on "Days of Our Lives", von Detten returned to series television with a guest appearance as a young boy trapped in a storm drain on a memorable episode of "ER" (NBC). He landed the regular role of Clu, a teenage boy on tour with his rock band manager mother and roadie father, in "So Weird". His Clu was a friend of Fi and Jack, the supernatural phenomena-tracking children of the band's singer, and along with them came across many unexplainable occurrences. In the fall of 1999, Von Detten premiered on the primetime network series "Odd Man Out", playing the lone male in the sitcom family, living with his mother, aunt and three sisters. Starring alongside Markie Post and Jessica Capshaw, this regular role afforded von Detten exceptional visibility and undoubtedly added to his legions of young fans.
On the big screen, von Detten essayed the role as the son of a slain police officer in the Chuck Norris action comedy "Top Dog" (1995) but is perhaps best remembered for a role in which he was never seen. He gave an appropriately menacing voice characterization to Sid, the sadistic, toy mangling young neighbor who nabs cowboy doll Woody and astronaut action figure Buzz Lightyear in the hit computer animated feature "Toy Story" (also 1995) The actor additionally did voice work in Disney's 1997 animated entry "Hercules".