After appearing opposite Woody Allen in "Take the Money and Run" (1969) as protagonist Virgil Starkwell's understanding wife, Margolin's screen appearances were rare, but she did show up in Allen's "Annie Hall" (1977) as his hyper-intellectual second wife and as the mysterious Ellie Fabain in Jonathan Demme's underrated noir "Last Embrace" (1979). TV kept her busier in the 70s, her telefilms including the interesting sci-fi dramas, "The Last Child" (1971) and "Planet Earth" (1974) and such socially conscious dramas as "The Triangle Factory Fire Scandal" (1979) and "The Plutonium Incident" (1980), the latter rather obviously modeled on the real-life story of Karen Silkwood. Margolin was notably less active during the 80s, but did act occasionally on TV and in several features; her made her final film appearance was in Ivan Reitman's "Ghostbusters II" (1989). She died of cancer in 1993.