John Stamos

After eight seasons as Uncle Jesse, a heartthrob with really bad hair, on the sitcom Full House, the Greek-American Stamos worked hard to shed his cutesy image by playing a variety of roles in a slew of low-rent cable TV-movies. He did, however, keep up his ladies'-man rep by dating a string of beauties, including Demi Moore, Paula Abdul and his now ex-wife, Rebecca Romijn. In between screen gigs, Stamos tapped into his musical talents, appearing on Broadway in a trio of musicals and playing drums for the Beach Boys. In the '00s he took more active control of his career by producing his own vehicles, including the short-lived crime romance Thieves and the constantly retooled sitcom Jake in Progress. When the latter was canceled, he picked up a role on ER.