Isaak's slim good looks and soft-spoken manner have earned him several small film roles, beginning as a fast-food clown in Jonathan Demme's "Married to the Mob" (1988) and a SWAT commander in Demme's "Silence of the Lambs" (1991). Isaak also appeared in the rockumentary "Let's Get Lost" (1988) and played an FBI agent in David Lynch's "Twin Peaks: Fire Walk With Me" (1992). But his acting career was pretty much a lark until 1994, when Bernardo Bertolucci cast him as the father of a child who may be the "Little Buddha". More supporting roles followed in the music-related films "Grace of My Heart", directed by Alison Anders, and "That Thing You Do!" (both 1996), which marked Tom Hanks' directorial debut. Also in 1996, Isaak made his TV acting debut as a children's library worker on the highly-hyped post-Super Bowl episode of NBC's hit sitcom "Friends".