Because of his widely publicized liberal views, Meredith found himself blacklisted in Hollywood for much of the 1950s. He returned to the Broadway stage acting in such seminal productions as "The Fourposter" (1952) and "The Teahouse of the August Moon" (1955) as the Okinawan interpreter Sakini. The actor donned 'yellowface' again for his return to features, portraying a Japanese supplier of goods to American soldiers in "Joe Butterfly" (1957). After scoring a stage triumph with "A Thurber Carnival" (1961), Meredith made "Advise and Consent" (1962), the first of six features with director Otto Preminger. Perhaps ironically, the actor played an informer who names Henry Fonda's Secretary of State designee as a member of the Communist Party. Other work for Preminger included playing a priest in the overblown "The Cardinal" (1963) and a judge in "Hurry Sundown" (1967).

Meredith earned back to back Oscar nominations in the mid-70s for his work as a former vaudeville star reduced to eking a living as a salesman in "The Day of the Locust" (1975) and as Sylvester Stallone's crusty trainer in "Rocky" (1976), a role he reprised in three of its four sequels. He remained active in small roles into the 90s, most notably as Jack Lemmon's randy father in "Grumpier Old Men" (1993) and its superior sequel "Grumpier Old Men" (1995).

TV buffs treasure his bookworm in the memorably ironic "Time Enough to Last" episode of "The Twilight Zone" from the early 60s. Baby boomers also fondly recall the actor as the monocled villain The Penguin in the campy 60s version of "Batman". Meredith's distinctive, sing-song rasp was also enlisted for countless commercial voice-overs and documentary narrations. Among his other more notable small screen roles was his Emmy-winning portrayal of attorney Joseph Welch in the above average biopic of Joseph McCarthy, "Tail Gunner Joe" (NBC, 1977).

In 1994, he published his autobiography, "So Far, So Good".