Mark Greene, 1994-2002
(Anthony Edwards)
Why Best? As the main character on ER for eight seasons, Dr. Mark Greene always put patients first. That became crystal clear in the very first episode when he turned down a cushy job at a private practice to be sleep-deprived and make a difference. When Edwards left the show in 2002, Greene’s death became one of the saddest moments on the medical show, leaving fans to wonder if the show would die along with his character. It was safe to assume Greene would never appear again, but last November, Edwards returned in a flashback, reminding us why we loved him so much in the first place.
KEEP READING: Dr. Amanda Lee was the worst!