The family film, which sees Depp voice a hapless lizard, beat competition in Britain, including Matt Damon’s The Adjustment Bureau and Unknown starring Liam Neeson, which pulled in close to $2 million.
Simon Pegg’s alien adventure Paul was fourth with $1.6 million (£1.1 million) and Oscar winner The King’s Speech stayed in the top five with takings of $1.5 million (£1 million).
Gnomeo & Juliet, I Am Number Four, True Grit, West Is West and Yogi Bear round out the U.K. top ten.
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