ROLE CALL: Pfeiffer, Penn and ‘Sam I Am’

We know what you might be thinking. But let us assure you, it has nothing to do with Dr. Seuss.

Yes, as the Hollywood Reporter says, Michelle Pfeiffer and Sean Penn are both in talks to star in the project “Sam I Am,” but the story is actually about a lawyer trying to win a custody case for a mentally disabled man.

And as you have no doubt guessed, Penn will play the man and Pfeiffer will play the legal eagle.

The project is aiming for a mid-January start in Los Angeles.

DOUBLE DOSE: Milla Jovovich is keeping herself busy these days. The actress, who last starred in “The Messenger: The Story of Joan of Arc,” has signed on to two indie films, to be shot back to back. The first one is called “Resident Evil,” a big-screen version of the popular video game. And the second is titled “You Stupid Man,” a romantic comedy about a man who just can’t get over his ex, the Reporter tells us.

‘SLAUGHTER’ HOUSE FOUR: Actress Kelly Lynch will join Ryan Gosling (“Remember the Titans“), David Morse (“The Green Mile“) and Clea DuVall (“Girl, Interrupted“) in the flick “Slaughter,” Daily Variety says. The project will be the feature- writing/directing debut for twin brothers Alex and Andrew Smith, whose short film “The Keening” was screened at this year’s Sundance Film Festival.

After the Hughes, the Coens and the Wachowskis, looks like another team of brothers is on the rise.