Director Paul Fieg and producer Judd Apatow team-up again for this comedy that stars Kristen Wiig as Annie, a romantically unattached failed bakery owner who fears she's losing her BFF, Lillian (Maya Rudolph), the best thing in her life, when Lillian announces she's gotten engaged. Annie's anxieties deepen as Lillian grows close to Helen (Rose Byrne), a wealthy and beautiful new friend who quickly assumes control of planning all the pre-wedding festivities. On top of the main storyline of a female friendship being torn apart, the movie adds a romantic storyline for Annie, who starts the film answering a booty call from the casually cruel yet undeniably handsome Ted (Jon Hamm), but develops a lovely flirtation with an Irish cop named Rhodes (Chris O'Dowd) after he pulls Annie over one night thinking she's driving drunk. As the low-self-esteem Annie sabotages this new possibility for love, she also feels the most important friendship in her life slipping away.