New Jersey's leading mutant superhero (unless Jon Bon Jovi counts) rises from the sludge to defend truth, justice, and radioactive waste once again in the third sequel to the 1985 cult sensation The Toxic Avenger. There's trouble brewing in the sleepy town of Tromaville when the Diaper Mafia, a group of inept but dangerous criminals, attempt an armed takeover of Tromaville's School for the Very Special for reasons best not contemplated. With the students held hostage, the Toxic Avenger (David Mattey) is called in to save the day, but a freak accident (as if there were any other kind in this movie) leads to an accident that creates an evil mirror version of Tromaville called Amortville; what's worse, heroic Toxie finds himself trapped in Amortville, while Tromaville is cursed with his wicked counterpart, Noxie. Can Toxie make it back to Tromaville and vanquish the villainous Noxie? Will the Diaper Mafia emerge triumphant? And who knew that the Supreme Being was a foul-mouthed dwarf? Citizen Toxie: The Toxic Avenger IV boasts one of Troma Team Pictures' typically eccentric supporting casts, including Corey Feldman, Ron Jeremy, Lisa Gaye, Hugh M. Hefner, Al Goldstein, Taylor Mead, Debbie Rochon, and Hank the Angry Dwarf.
~ Mark Deming, All Movie Guide