This grim sci-fi film presents a dim view of the near future in which humanity has been decimated by a virulent plague. The survivors are rigidly divided into those who are plague-free and those who are dying. The former live in heavily-guarded areas and have most of the wealth and power, while the latter are quarantined. A few people have a fatal but not contagious mutation of the virus. These are the Zero Men, and during their lives they are able to move in an out of the different zones; some of them are mercenaries and when the daughter of a prominent industrialist is kidnapped and taken to the plague zone, it is up to one of these terminally ill soldiers of fortune to save her.