A vain gambler (Fabio Testi), a pregnant prostitute (Lynne Frederick), a bumbling alcoholic (Michael J. Pollard) and a man who claims to see ghosts (Harry Baird) become unlikely traveling companions in this unusual spaghetti Western from notorious Italian horror director Lucio Fulci. The only survivors of a frontier-town massacre staged to rid the once-lawful town of its overpowering criminal element, the quartet ride the Western trail in a last-ditch bid to reach the next populated area and get back on their feet. Soon drawing the attention of a trigger-happy bandit named Chaco (Tomas Milian), the four cautiously accept him into the fold when Chaco displays a remarkable talent for hunting. When their newfound friend tortures the foursome and leaves them for dead after feeding them hallucinogens, the remaining survivors' desperate bid for survival leads them to take shelter in a ramshackle mining town inhabited only by men of questionable honor. As the birth of her child draws closer, prostitute Bunny (Frederick) looks to suave gambler Stubby (Testi) for the love and support to bring her child into the world. Though the men of the town reluctantly band together to aid Bunny in the birth of her baby, Stubby finds himself torn between the prospect of fatherhood and his unquenchable thirst for revenge against the supremely evil Chaco.