Written and directed by Italian filmmaker Pupi Avati, Il Cuore Altrove is a romantic drama centering on Nello, a college Humanities teacher played by Neri Marcoré. His parents are well-to-do tailors who work for the Pope, and they don't approve of Nello's line of work. At their urging, Nello moves to Bologna where he meets and falls in love with Angela, a local blind girl played by Vanessa Incontrada. But their relationship isn't a simple one. Her parents don't believe that a simple teacher is worthy of their daughter, his parents protest because she is blind, and her ex-boyfriend may not be completely out of the picture. Adding one more wrench in the gears is a doctor who might be able to restore Angela's sight, leading Nello to wonder if she'll still feel for him if she isn't blind. Giancarlo Gianinni also stars as Nello's father.