With his self-reflexive documentary Indestructible, director Ben Byer - a victim of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease - films his own emotional and spiritual journey-of-self-discovery (and physical deterioration) as he searches, in vain, for an ALS cure before the window closes on his life. This almost painfully intimate and revealing film finds single father Byer faced with an estimated lifespan of between 2-5 years. He then makes a long, desperate journey to Greece and China, where he will undergo an innovative procedure that he hopes will end the disease once and for all. Byer then returns home to be with his son, and rapidly arrives at the conclusion that the treatment has failed. Throughout it all, Byer exudes an ebullient and celebratory attitude, and experiences a series of unspeakable joys and sorrows, carrying the audience along with him.