In this drama, set in Italy during 1889, a young doctor meets and falls for the daughter of a renowned medical professor. The professor does not approve of the affair and suggests that the young medic leave Rome. The physician then goes to Obetello, and there he discovers a radical, but successful treatment for malaria. Trouble ensues when he spurns the advances of an amorous neighbor. For revenge she begins blaming the current malaria epidemic upon him. As a result he is tried and sentenced to four years in prison for using unorthodox methods. His medical license is also revoked. In jail, he is promoted to orderly. He promptly inoculates himself against the dread disease using his own treatment. He soon proves his innocence and is acquitted of all crimes. He then returns to Rome to marry his true love.