When three sisters venture deep into the backwoods to visit the home recently left to them by their long lost grandfather, they are stalked by a psychotic family of murderous rednecks who have taken up residence in the home and who have no plans of giving it up. Their grandfather was recently killed in the most gruesome manner imaginable, and the three sisters are stunned to learn that they are the sole heirs to his sprawling estate. After rounding up a group of close friends, the girls set out for the hills in order to explore the house and have a little fun. The good times come to an abrupt end, however, when a family of inbred maniacs emerges with a lethal grudge and a lingering thirst for blood.