Another "torn from today's headlines" crime drama, Las Vegas Shakedown stars Dennis O'Keefe as honest casino operator Joe Barnes. When not fending off gangster boss Sirago (Thomas Gomez), who wants a big piece of the action, Barnes endeavors to dodge pretty schoolteacher Julia Rae (Colleen Gray), who is writing a thesis on the futility of gambling. The episodic storyline occasionally cuts away to small-town banker Raff (Charles Winninger), who tries to have a little fun at the gaming tables despite the interference of his wife (Elizabeth Patterson), and a bevy of attractive divorcees who've set their cap for Barnes. Filmed on location, Las Vegas Shakedown comes to a head when the disgruntled Sirago resorts to all-out violence to take over Barnes' operation.