Though its PG-13 rating is well earned, Look Who's Talking has some elements that might appeal to a family audience. Chief among them, of course, is the "talking baby" protagonist. The product of an extramarital affair, infant Mikey (played by several different babies, and given voice by Bruce Willis) is a cynical, sarcastic observer of his new world. Mikey's mother, Kirstie Alley, having been dumped by her married lover George Segal, searches high and low for a new father for her baby. Of course, the perfect daddy is right under her nose all the time: cab driver John Travolta, who was on the scene when she went into labor on the sidewalk. The best moments in Look Who's Talking include Ms. Alley's imaginary flights of fancy, and the misadventures of Mikey as he progresses from sperm to reluctant newborn (his violent vocal protests against being yanked from the womb are worth the admission price in themselves). Look Who's Talking has spawned two sequels, neither of which are as charming or disarming as the original.
~ Hal Erickson, All Movie Guide