Two young lovers go on the run from the law after a convenience store robbery goes bad in this road movie. Love and a .45 centers on philosophically inclined thief Watty Watts (Gil Bellows), who believes in a little robbery but not real violence. An ill-advised collaboration with a crazed, drugged-out biker (Rory Cochrane) ends badly, however, forcing Watty to go on the run. His girlfriend Starlene (Renee Zellweger) joins him, and the two become media darlings thanks to television coverage of their flight from the law. First-time director C.M. Talkington's combination of violence and ironic attitude recalls both 1970s crime dramas and Quentin Tarantino's violent, quirky takes on the genre. However, the film's warmed-over feel may be redeemed by its irreverent tone and appealing performances, including a self-parodying appearance by Peter Fonda.