Canine comic strip star Marmaduke leaps to the big screen with this family-friendly comedy starring Owen Wilson as the voice of the Great Dane. Also lending their voices to the 20th Century Fox production are Steve Coogan, pop star Fergie, George Lopez, and the brotherly duo of Damon and Marlon Wayans, with William H. Macy and Judy Greer heading up the human cast.
~ Jeremy Wheeler, All Movie Guide