Tony lives in Ontario, but he has relatives all over the eastern part of the U.S. and Canada. Since he has been earning money by running marijuana from Pittsburgh to Canada, he's been avoiding them, but when his beloved grandfather bids him from his deathbed to take care of his wife, Tony's grandmother, he reluctantly agrees to do so. By now, he has already messed up a delivery for a dealer who is now gunning for him, so when his feisty grandmother proposes suing the American mining company grandpa worked with for causing him to die of black lung disease, he readily agrees to take her to Pittsburgh to file her suit. As they travel, these two angry and distrustful relations bicker and quarrel a lot but also uncover their true value to one another.