After losing his license to work as a surgeon, synthetic-heroin addict Eugene Sands (David Duchovny) is on a downward spiral into the Los Angeles drug scene. One night, someone is shot in a bar, and Sands performs a life-saving medical maneuver on the spot. Word travels fast. A few days later, a limo drops him off at the Malibu den of counterfeiter-smuggler Raymond Blossom (Timothy Hutton) and his cupid-lipped moll Claire (Angelina Jolie). The bleach-haired Blossom needs someone to stitch up his hemorrhaging henchmen so they won't wind up answering questions at a hospital. He sees Sands as the ideal man to stop the flow of information and blood. It's a deal with the devil, but Sands accepts. Meanwhile, Claire has her eye on Sands, and FBI agent Gage (Michael Massee) has plans to bring down Blossom.