The second and third novels in author Anne Rice's popular book series The Vampire Chronicles provide the inspiration for this horror sequel starring ill-fated actress and recording artist Aaliyah, who was killed in an airplane crash before the film's release. Stuart Townsend is the vampire Lestat, who has awakened from a century-long slumber and turned his considerable energy to rock music. His vampirism identity mistaken for a gothic hard rock publicity stunt along the lines of Kiss or Marilyn Manson, he quickly becomes a pop music sensation. Lestat's powerful music reaches the ear of the slumbering Akasha (Aaliyah), the millennia-old "queen of the vampires" who was the first immortal bloodsucker. Akasha is soon free and embarking on a quest to seize control of the world with Lestat at her side. In the meantime, Lestat becomes an object of fascination for Jesse Reeves (Marguerite Moreau), member of a secret order studying the supernatural called the Talamasca, and a band of ancient vampires come together in an effort to stop Akasha, even though her destruction could potentially cause their own deaths. Queen of the Damned co-stars Lena Olin and Vincent Perez.