An unemployed New York doctor with a suspended license and few prospects for the future travels to Jamaica to care for the ailing brother of a wealthy landowner, only to make a horrifying discovery regarding the ailing man in director Avi Nesher's contemporary re-imagining of Jacques Tourneur's I Walked with a Zombie. Dr. Alice Dodgson (Jennifer Grey) is an open-minded oncologist whose experiments with an unapproved drug have just cost her patient his life and found her license to practice medicine promptly revoked. Subsequently summoned to Jamaica by affluent American Paul Claybourne (Craig Sheffer), Dr. Dodgson is assigned the duty of caring for Claybourne's cancer-stricken brother, Wesley (Daniel Lapaine). Though Dr. Dodgson at first dismisses the local tales of zombies and possession as mere superstition while she cares for the increasingly despondent Wesley, her growing feelings for her patient soon bring her to the realization that Wesley is not suffering from cancer after all, but the powerful curse of a local witch doctor. Now, in order to save the man that she has come to love, Dr. Dodgson must uncover the secret behind the potentially fatal curse while facing off against a vicious voodoo queen with the power to destroy anyone and anything in her path.