When a diverse group of lifelong friends comes together to celebrate the marriage of devoted couple Elise (Amy Adams) and Michael (Adam Garcia), the mixed-up relationships of the past pave the road to a weekend no one is likely to soon forget in the feature debut from filmmaker Matthew Cole Weiss. The setting is Los Angeles, CA, and the event is the wedding between a man and a woman who always seemed destined to be together. Unfortunately, all relationships can't be as healthy as Elise and Michael's is, and though best man and maid of honor Rich (Aaron Stanford) and Samantha (Melissa Sagemiller) seem to be preparing to take the plunge, the same certainly cannot be said for neurotic actress Lana (Mena Suvari). A free-spirited soul who has experienced flings with a variety of wedding attendees including the hapless Pockets (Jon Abrahams), alcoholic actor Simon (James Van Der Beek), and manic children's television program host Donovan (Ethan Embry), Lana attempts to sort out her past flings as lovelorn agent Quentin (Colin Hanks) pines for the bride's sister and the estranged father of the groom attempts to reconnect with his long-lost son.