Director Wes Craven, who went on to fame as the force behind blockbuster horror films such as A Nightmare on Elm Street, departed from his favorite genre to film this unique cult classic -- a spoof on the mad scientist movies of the 1950s. Adrienne Barbeau stars as Alice Cable, a government agent sent to replace a man who has disappeared while guarding a secret experimental lab in the middle of the Louisiana bayous. Dressed in heels and a skirt, Cable professes unease at her strange new surroundings, but she is soon wooed by Dr. Alec Holland (Ray Wise). Holland is working on a concoction that combines plant and animal cells. Arcane (Louis Jourdan) is the criminal mastermind who is trying to steal the secret recipe for the potion. When Arcane and his mercenaries break into the government camp, they kill Holland's sister Linda (Nannette Brown) and the scientist is accidentally doused with his own formula and bursts into flames, then dives into the swamp. Arcane's men pursue Cable, but she is rescued by a mysterious green man. It takes several rescues for her to understand that the Swamp Thing (Dick Durock) is Dr. Holland, transformed by his own formula.
~ Michael Betzold, All Movie Guide