The stars have aligned in an ominous sign, and as a legion of malevolent monsters descends upon New York City to wage war against humanity, the only thing that stands between humankind and certain destruction are four wisecracking turtles with a flair for martial arts and a hearty appetite for pizza. Kevin Eastman and Peter Laird's "heroes in a half-shell" return to defend the world against an interstellar threat that comes just once every 3,000 years in a computer-animated action comedy that marked the final film role of Japanese screen legend Mako -- here providing the voice of the eternally wise Master Splinter. Buffy the Vampire Slayer star Sarah Michelle Gellar lends her voice to the role of the turtles' technical-services worker, April; Fantastic Four's Chris Evans assumes the role of hockey-loving crimefighter Casey Jones; Memoirs of a Geisha star Zhang Ziyi steps in as villainous Foot Ninjas leader Karai; and Star Trek: The Next Generation captain Patrick Stewart voices malevolent tech industrialist Max Winters -- a mortal man whose hunger for profit and power may spell doom for all humanity.