Underground film icon Giuseppe Andrews stars as a sexually frustrated, half-Latino speed dealer whose rampant paranoia is about to get the best of him in director Eric Johnson's tense, hallucinogenic thriller Tweek City. Fired from his job at a Bay Area computer company, San Francisco speed slinger Bill Jenson (Andrews) seeks solace in the company of punk-rock porn connoisseur Jerm (Keith Brunsmann) -- a White Trash Debutantes fanatic. Jerm, however, becomes completely useless when he takes Bill to a punk rock concert, then stage dives and severely injures himself -- leaving Bill to fend for himself and to focus on what troubles him the most: the loss of his lifelong love, Sharon (Elizabeth Bogush). Life goes on, though, and these days Sharon is set to marry another man. As the wedding date draws near and Bill's tenuous grip on reality slowly begins to slip, the lovelorn addict embarks on a drug-soaked bender of epic proportions before he sets his sights on the ceremony and determines to stop the union at all costs.
~ Jason Buchanan, All Movie Guide