Former pony express riders John Blair (John Wayne) and Larry Adams (Lane Chandler) don't buy the Brooklyn Bridge in this Republic Western, but the two greenhorns instead purchase a dilapidated stage line to a ghost town. While the unscrupulous seller, "Honest Cal" Drake (Douglas Cosgrove), count his loot, John and Larry learn that Crescent City is inhabited by Rocky (Lew Kelly), who claims to be mayor, postmaster, and sheriff, and Dr. William Forsythe (Sam Flint), a fellow victim of the duplicitous Drake. But despite its current condition, Crescent City has rich potential, especially if the newcomers can obtain a $25,000 government mail subsidy, the winner of which will be determined by a stagecoach race between nearby Buchanan City and Sacramento. Winds of the Wasteland was filmed on location in the Sierra Mountains and in the Sacramento Valley. Watch for future Universal star Jon Hall as one of John Wayne's pony express colleagues.
~ Hans J. Wollstein, All Movie Guide