So little was known about mental illness in 1908 that Vitagraph could be forgiven the sweeping generalizations in its one-reel drama At Home at Last. Having lost her son, a young mother goes temporarily mad with grief. An understanding doctor suggests that the "only cure" for the woman's dementia is to adopt another child. The woman promptly brings an orphaned girl into the home, only to end up resenting the girl's presence, feeling that no one can replace her son. Gradually (but not too gradually, since the film is only about nine minutes long), the dewey-eyed girl wins the heart of the grieving mother.

~ Hal Erickson, All Movie Guide