The couple, which has been married since 2005, has teamed up for numerous projects, including the actor's latest blockbuster, Sherlock Holmes.
The Iron Man star insists he is comfortable taking orders from his wife on set and he appreciates spending his working days with her.
He tells The Globe tabloid, "I know my place! We love working together. Making movies is so (sic) energy and time-consuming that it takes you away from your real life for big chunks of time. So I get to escape with her as opposed to from her."