The actresses will team up again on a 2010 episode of the U.S. show.
Cox tells TVGuideMagazine.com, "She'll (Kudrow) play a dermatologist that my character can't stop going to even though (she's) mean to me."
Cox's pal and fellow former Friends co-star Jennifer Aniston teamed up with the actress for an episode of her last TV series, Dirt.