William Petersen has joined the cast of Tony Kaye’s indie drama Detachment.

Along with CSI’s erstwhile Grissom, Mad Men’s Christina Hendricks has come on board as well as Lucy Liu.

According to The Hollywood Reporter, the high school-set drama centers on a detached substitute teacher who becomes invested in the students and teachers at the troubled school where he works and grows close to a homeless teen who is also a prostitute.

Petersen will play a Vietnam veteran who teaches history; Hendricks will play a teacher who may be a romantic interest for Adrien Brody’s lead character; and Liu will play a school psychologist who grows frustrated with her students' incompetence.

Also starring in the picture are Bryan Cranston, James Caan and Marcia Gay Harden.

The script is by Carl Lund, with Bingo Gubelmann, Austin Stark, Benji Kohn and Greg Shapiro producing. Shooting recently began in New York.

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